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Acute Liver Failure (ALF): A Race Against Time Acute Liver Failure (ALF) is a life-threatening condition characterized by rapid deterioration of liver function in a previously healthy individual, leading to coagulopathy (INR ≥1.5) and hepatic encephalopathy within days to weeks. Unlike chronic liver disease, ALF requires urgent recognition and intervention, often determining life or death within hours. Common Causes of ALF in India & Globally: 🔹 Viral Hepatitis (Hepatitis A, B, E) – Leading cause in India. 🔹 Drug-Induced Liver Injury (DILI) – Paracetamol overdose (Western countries) & herbal/alternative medicines (India). 🔹 Autoimmune Hepatitis & Wilson’s Disease – Often missed but crucial to diagnose early. 🔹 Ischemic Hepatitis & Sepsis-Related Injury – Seen in critically ill patients. How ALF Progresses – The Danger of Delay: ⚠️ Stage 1: Mild Confusion, Fatigue – Patients may ignore symptoms. ⚠️ Stage 2: Drowsiness, Jaundice, INR > 2.0 – Liver function worsening, ICU needed. ⚠️ Stage 3: Severe Encephalopathy, Multi-Organ Dysfunction – High mortality if not treated aggressively. ALF Management: The Critical Approach ✔️ Early ICU Admission – Multisystem support (hepatic, renal, neurological). ✔️ Specific Therapy: NAC for paracetamol toxicity, steroids for autoimmune ALF. ✔️ Liver Transplant – The Last Resort: Survival >70% if done in time. Why Choose Dr. Chetan Kalal for ALF Care? 🏥 Mumbai’s Leading Hepatologist & Transplant Expert 🔬 Pioneer in Advanced ALF Management & Liver ICU Protocols ⚕️ High Success Rates in Managing Complex Liver Cases 💡 Every Minute Counts in ALF. Seek Expert Care Immediately! #DrChetanKalal #BestHepatologistInMumbai #LiverFailure #AcuteLiverFailure #LiverTransplant #HepatologyExpert #LiverICU #SaveLives #besthepatologistindia